Toxicities terms for Skin and subcutaneous tissue disorders

Alopecia

A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location.

Body odor

A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body.

Bullous dermatitis

A disorder characterized by inflammation of the skin characterized by the presence of bullae which are filled with fluid.

Dry skin

A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture.

Eczema

A disorder characterized by skin which becomes itchy, red, inflamed, crusty, thick, scaly, and/or forms blisters.

Erythema multiforme

A disorder characterized by target lesions (a pink-red ring around a pale center).

Erythroderma

A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area.

Subcutaneous emphysema

A disorder characterized by air in the subcutaneous tissue.

Telangiectasia

A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes.

Toxic epidermal necrolysis

A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.

Urticaria

A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined red margins.

Skin and subcutaneous tissue disorders - Other, specify

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Stevens-Johnson syndrome

A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.

Skin ulceration

A disorder characterized by a circumscribed, erosive lesion on the skin.

Skin induration

A disorder characterized by an area of hardness in the skin.

Skin hypopigmentation

A disorder characterized by loss of skin pigment (e.g., vitiligo).

Fat atrophy

A disorder characterized by shrinking of adipose tissue.

Hair color changes

A disorder characterized by change in hair color or loss of normal pigmentation.

Hair texture abnormal

A disorder characterized by a change in the way the hair feels.

Hirsutism

A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen).

Hyperhidrosis

A disorder characterized by excessive sweating.

Hyperkeratosis

A disorder characterized by a thickening of the outer layer of the skin.

Hypertrichosis

A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race.

Hypohidrosis

A disorder characterized by reduced sweating.

Lipohypertrophy

A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin.

Nail changes

A disorder characterized by a change in the nails.

Nail discoloration

A disorder characterized by a change in the color of the nail plate.

Nail loss

A disorder characterized by loss of all or a portion of the nail.

Nail ridging

A disorder characterized by vertical or horizontal ridges on the nails.

Pain of skin

A disorder characterized by a sensation of marked discomfort in the skin.

Palmar-plantar erythrodysesthesia syndrome

A disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet. Also known as Hand-Foot Syndrome.

Photosensitivity

A disorder characterized by an increase in sensitivity of the skin to light.

Pruritus

A disorder characterized by an intense itching sensation.

Purpura

A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color.

Rash acneiform

A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back.

Rash maculo-papular

A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritis.

Scalp pain

A disorder characterized by a sensation of marked discomfort in the skin covering the top and the back of the head.

Skin atrophy

A disorder characterized by the degeneration and thinning of the epidermis and dermis.

Skin hyperpigmentation

A disorder characterized by darkening of the skin due to excessive melanin deposition.