Toxicities terms for Hepatobiliary disorders

Bile duct stenosis

A disorder characterized by a narrowing of the lumen of the bile duct.

Biliary fistula

A disorder characterized by an abnormal communication between the bile ducts and another organ or anatomic site.

Budd-Chiari syndrome

A disorder characterized by occlusion of the hepatic veins and typically presents with abdominal pain, ascites and hepatomegaly.

Cholecystitis

A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones.

Gallbladder fistula

A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site.

Gallbladder necrosis

A disorder characterized by a necrotic process occurring in the gallbladder.

Gallbladder obstruction

A disorder characterized by blockage of the normal flow of the contents of the gallbladder.

Gallbladder pain

A disorder characterized by a sensation of marked discomfort in the gallbladder region.

Hepatic failure

A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, alkaline phosphatase, aminotransferase, and/or prolongation of prothrombin time (INR.) Drug-induced liever injury (DILI) as defined by Hy's Law.

Hepatic hemorrhage

A disorder characterized by bleeding from the liver.

Hepatic necrosis

A disorder characterized by a necrotic process occurring in the hepatic parenchyma.

Hepatic pain

A disorder characterized by a sensation of marked discomfort in the liver region.

Perforation bile duct

A disorder characterized by a rupture in the wall of the extrahepatic or intrahepatic bile duct.

Portal hypertension

A disorder characterized by an increase in blood pressure in the portal venous system.

Portal vein thrombosis

A disorder characterized by the formation of a thrombus (blood clot) in the portal vein.

Sinusoidal obstruction syndrome

A disorder characterized by severe hepatic injury as a result of the blood vessels of the liver becoming inflamed and/or blocked.

Hepatobiliary disorders -Other, specify

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Gallbladder perforation

A disorder characterized by a rupture in the gallbladder wall.